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Latest news from trusted sources around the world
De novo design of cysteine proteases
Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11143-wDe novo-designed enzymes use an activated cysteine nucleophile to hydrolyse polypeptide backbones in a sequence-dependent manner.
Evaluating space-based methane detection through a one-year blind test
Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11115-0A year-long single-blind study shows that multiple satellites can accurately detect and quantify methane point-source emissions.
Capillary-selective vasodilation through myosin inhibition halts ischaemic cascades
Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11171-6R(+)2501 reverses capillary no-reflow by relaxing pericytes, restoring microvascular perfusion and improving survival in animal models of myocardial infarction …
Parity-dependent coupling of molecular spin chains to a superconductor
Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11117-yScanning tunnelling spectroscopy shows that the fractional spin-1/2 end states of molecular Haldane chains couple differently to a superconducting …
Competing mechanisms toughen bcc binary and medium-entropy alloys at 20 K
Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11065-7The mechanical properties of medium-entropy alloys at 20 K show a plateau in tensile yield strength and fracture toughness …
Modelling mouse embryogenesis from chemically induced totipotent stem cells
Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11164-5A mouse embryo model derived from chemically induced totipotent-like stem cells progresses through key developmental milestones, including gastrulation, embryonic …
<i>Elp1</i> is required for myeloid differentiation and brain repopulation
Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11112-3Primary cultured haematopoietic stem and progenitor cells are used to analyse the molecular mechanisms of brain myeloid differentiation, and …
Engineered TYK2 dependence enables myeloid-selective IL-10 receptor agonism
Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11176-1A tetravalent nanobody-based myeloid-selective IL-10 receptor agonist recapitulates IL-10’s potent suppression of monocytes, macrophages and dendritic cells while avoiding …
Global conservation area coverage substantially exceeds current estimates
Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11157-4A globally representative sample of 25 countries and territories indicates that conservation areas cover 26.81% of the land, much …
Evidence for multi-Li<sup>+</sup> clustering in lithium-ion battery electrolytes
Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11138-7Machine-learning-enabled atomistic simulations, spectroscopy, electrochemical data and quantum-chemical calculations reveal previously unstudied multi-lithium-ion complexes without bound anions, improving understanding …
Smartwatch health data are piling up. How can doctors keep pace?
Nature, Published online: 14 October 2026; doi:10.1038/d41586-026-03203-yTo harness the full value of wearable devices for monitoring and diagnosing medical conditions, protocols must be established.
Overlooked brown fat in our bodies linked to wide range of health …
Nature, Published online: 14 October 2026; doi:10.1038/d41586-026-03302-wMassive study of more than 100,000 people finds surprising connection between ‘good’ body fat and improved mental health.
Structural basis of ligand recognition and gating in mosquito IRs
Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11239-3Structural basis of ligand recognition and gating in mosquito IRs
Daily briefing: China’s extraordinary rise in science
Nature, Published online: 14 October 2026; doi:10.1038/d41586-026-03322-6Explore China’s efforts to grow its scientific and technological might. Plus, how butterflies trick the eye and what could …
How early tetrapods got their neck
Nature, Published online: 14 October 2026; doi:10.1038/d41586-026-03061-8As fish evolved into four-limbed creatures, their skull separated from their shoulders to form a neck. Now we learn …
Hydrogels and MRI: meet three biomedical engineers reshaping health care
Nature, Published online: 14 October 2026; doi:10.1038/d41586-026-03205-wResearchers are making great advances across medical disciplines, using a wide range of tools and processes.
Alveolar stem cells go beyond making gas-exchange cells to repair damaged airways
Nature, Published online: 14 October 2026; doi:10.1038/d41586-026-03085-0Alveolar type 2 (AT2) cells are the stem cells of the lung’s air sacs and are responsible for maintaining …
‘Incredible’: bleached corals thrive within days when touching healthy neighbour
Nature, Published online: 14 October 2026; doi:10.1038/d41586-026-03266-xA coral fragment can form a tissue bridge with a dying counterpart — and provide it with crucial microalgae.
Protecting nature means valuing biodiversity
Nature, Published online: 14 October 2026; doi:10.1038/d41586-026-03219-4Appeals for extra money are failing. Fundamental changes are needed to safeguard the planet for future generations.
Large blind test of methane-detecting satellites lends credibility to emissions data
Nature, Published online: 14 October 2026; doi:10.1038/d41586-026-03075-2Twelve methane-sensing satellites were tested for their accuracy in measuring controlled-release events in the Arizona desert over a year-long …
Some Jurassic period birds were flightless
Nature, Published online: 14 October 2026; doi:10.1038/d41586-026-02645-8The fossil discovery of an early avian ancestor in China reveals that flightless birds lived alongside the known flying …
Is this idea from AI or humans? A detector claims it can …
Nature, Published online: 14 October 2026; doi:10.1038/d41586-026-03247-0A tool called IdeaLens helps to judge whether concepts — rather than just writing — in scientific papers are …
Lay of the land: terrestrial conservation efforts cover a wider area than …
Nature, Published online: 14 October 2026; doi:10.1038/d41586-026-03081-4Governments around the world have pledged to conserve 30% of the terrestrial realm by 2030, but official data suggest …
<b>The world is closer to a major conservation target than scientists thought</b>
Nature, Published online: 14 October 2026; doi:10.1038/d41586-026-03307-5Analysis suggests number of protected areas is hugely underestimated but biodiversity is still in peril — plus, a huge …
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