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Latest news from trusted sources around the world
mRNA vaccines engage unconventional pathways in CD8<sup>+</sup> T cell priming
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10353-6mRNA–lipid-nanoparticle vaccines do not require type 1 conventional dendritic (cDC1) cells or the WDFY4-dependent cross-presentation pathway for CD8+ T …
Tumour promotion through the lens of evolution
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10386-xThis Review revisits tumour initiation and promotion in light of clonal diversity and the presence of cancer driver mutations …
Ancient DNA reveals pervasive directional selection across West Eurasia
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10358-1Analysis of 15,836 ancient West Eurasian genomes reveals hundreds of instances of directional selection, showing that sustained changes in …
Brainwide blood volume reflects opposing neural populations
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10350-9Combined functional ultrasound imaging and Neuropixels recording of mouse brains identify two neuronal populations with opposing arousal-related activity and …
Identifying the topographic signature of early Martian oceans
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10381-2Shelves rather than shorelines may be better topographic indicators of oceans on Earth and Mars.
Linear RAG scanning mediates editing of Igκ variable region repertoires
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10362-5Studies explaining the secondary Igk recombination mechanism are described and Cer/Sis deletion and/or displacement is implicated as a developmental …
Giant cancer study reveals effectiveness of ‘off label’ treatments
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-01241-0Genomics-guided trial could increase options for people undergoing cancer therapy — plus, a landmark ancient-genome study reveals natural selection …
Author Correction: HER2 expression identifies dynamic functional states within circulating breast cancer …
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10519-2Author Correction: HER2 expression identifies dynamic functional states within circulating breast cancer cells
Monolithic 3D integration of tantalum pentoxide nonlinear photonics
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10379-wMonolithic three-dimensional (3D) integration of tantalum pentoxide on a lithium niobate substrate enables scalable, multifunctional photonic systems and the …
Carbonyl swapping converts cyclic ketones to saturated heterocycles
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10508-5Carbonyl swapping converts cyclic ketones to saturated heterocycles
Editorial Expression of Concern: Creation of human tumour cells with defined genetic …
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10504-9Editorial Expression of Concern: Creation of human tumour cells with defined genetic elements
Retraction Note: The hidden fitness of the male zebra finch courtship song
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10483-xRetraction Note: The hidden fitness of the male zebra finch courtship song
Cytoplasmic lattices are megadalton storage complexes in mammalian oocytes
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10513-8Cytoplasmic lattices are megadalton storage complexes in mammalian oocytes
Can China’s Great Green Wall shape efforts to keep the world’s deserts …
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-01102-wGrand anti-desertification schemes often fail when trees die and funding dries up — yet one project has broken the …
What China’s Great Green Wall can teach the world
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-01195-3Efforts to boost tree cover and restore degraded land globally need stable funding and time to learn from failure.
Dozens of AI disease-prediction models were trained on dubious data
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-00697-4The models are designed to predict someone’s risk of diabetes or stroke. A few might already have been used …
Imaging interface-controlled bulk oxygen spillover
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10324-xIn situ microscopic single-particle imaging demonstrates the significance of rationally engineered metal–support interfaces for activating the oxygen in bulk …
Daily briefing: The air is full of DNA — here’s what it …
Nature, Published online: 14 April 2026; doi:10.1038/d41586-026-01238-9Researchers are using airborne DNA to get snapshots of the make up of ecosystems. Plus, what scientists in Hungary …
Saving face: why facial scars are smaller than back scars
Nature, Published online: 14 April 2026; doi:10.1038/d41586-026-01044-3Facial wounds heal with less scarring than do comparable ones on the back. The reason relates to differences in …
Boycott of major AI conference exposes a growing US–China divide
Nature, Published online: 14 April 2026; doi:10.1038/d41586-026-01058-xChina-based researchers make up more than half of all lead authors at NeurIPS.
What Orbán’s fall from power means for research around the world
Nature, Published online: 14 April 2026; doi:10.1038/d41586-026-01225-0Hungary’s new leader has promised to restore the system of checks and balances — but researchers say that rebuilding …
NSF awards record number of coveted PhD fellowships in surprise move
Nature, Published online: 14 April 2026; doi:10.1038/d41586-026-01119-1Quantum science and AI research are big winners just a year after the US funding giant slashed its Graduate …
Stop the ‘space race’: space exploration must be a shared human endeavour
Nature, Published online: 14 April 2026; doi:10.1038/d41586-026-01194-4Although led by NASA, Artemis II wasn’t just a US achievement; the mission was a collaborative effort. Long may …
AI needs solid botanical data more than ever
Nature, Published online: 14 April 2026; doi:10.1038/d41586-026-01196-2An artificial-intelligence revolution in biotechnology won’t get far without human taxonomic expertise — and that’s under threat.
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