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The protein carriers of hundreds of lipids have been identified
Nature, Published online: 25 February 2026; doi:10.1038/d41586-026-00570-4Different types of lipid molecule are transported around the cell by lipid-transfer proteins. Biochemical approaches have been adapted to …
We need a global assessment of avoidable climate-change risks
Nature, Published online: 25 February 2026; doi:10.1038/d41586-026-00544-6To understand the urgency of emissions reductions, policymakers and citizens need a full analysis of what is at stake.
Stem cells provide a potent treatment for frailty
Nature, Published online: 25 February 2026; doi:10.1038/d41586-026-00584-yElderly people with frailty, which affects up to one-quarter of over-50s, increased their endurance after a single dose of …
EU leaders should not rush to revamp green-hydrogen rules
Nature, Published online: 25 February 2026; doi:10.1038/d41586-026-00560-6Some policymakers think that climate-friendly policies are impeding the adoption of green hydrogen. They should ask scientists to review …
Entanglement-assisted non-local optical interferometry in a quantum network
Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10171-wEntangled quantum memories are used in a quantum network of silicon–vacancy centres in diamond nanocavities to experimentally perform non-local …
Human hippocampal neurogenesis in adulthood, ageing and Alzheimer’s disease
Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10169-4Mapping of neurogenesis in human hippocampi across ages and different cognitive abilities using multiomic single-cell sequencing reveals distinct signatures …
Uncovering origins of heterogeneous superconductivity in La<sub>3</sub>Ni<sub>2</sub>O<sub>7</sub>
Nature, Published online: 25 February 2026; doi:10.1038/s41586-025-10095-xWide-field quantum sensing shows μm-scale inhomogeneous superconductivity in high-pressure La3Ni2O7, linking local diamagnetic response to stress and stoichiometry and …
Functional dissection of complex trait variants at single-nucleotide resolution
Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10121-6Massively parallel reporter assays across five cell types identify thousands of causal, noncoding regulatory variants among 220,000 loci, revealing …
CLCC1 governs ER bilayer equilibration to maintain lipid homeostasis
Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10161-yPhospholipid scrambling at the endoplasmic reticulum is essential for establishing a dynamic equilibrium to maintain cellular homeostasis.
CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly
Nature, Published online: 25 February 2026; doi:10.1038/s41586-025-10064-4CRISPR–Cas9 screening identifies CLCC1 as a factor that increases neutral lipid flux to prevent hepatic steatosis and promotes nuclear …
Coral microbiomes as reservoirs of unknown genomic and biosynthetic diversity
Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10159-6Reconstructing microbial genomes from 820 reef-building corals collected at 99 reefs across 32 islands throughout the Pacific Ocean highlights …
Argentine fossil rewrites evolutionary history of a baffling dinosaur clade
Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10194-3A skeleton of the alvarezsauroid Alnashetri cerropoliciensis—representing a highly complete alvarezsauroid skeleton from South America—provides evidence on the evolution …
Hydrofluorocarbon electrolytes for energy-dense and low-temperature batteries
Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10210-6A method using hydrofluorocarbon electrolytes for synthesizing alkanes with monofluorinated structures is described, yielding a pathway for manufacturing lithium-metal …
Field-free full switching of chiral antiferromagnetic order
Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10175-6An Mn3Sn homo-junction enables efficient field-free full switching of chiral antiferromagnets with greatly reduced power consumption, advancing their potential …
Rewiring an E3 ligase enhances cold resilience and phosphate use in maize
Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10142-1The E3 ubiquitin ligase NLA postively regulates cold tolerance and negatively regulates phosphate uptake in maize, and a genetically …
A disease model resource reveals core principles of tissue-specific cancer evolution
Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10187-2The Mouse Cancer Cell line Atlas (MCCA) provides major advances towards a mechanistic understanding of cancer genomes.
OR7A10 GPCR engineering boosts CAR-NK therapy against solid tumours
Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10149-8The identification of ‘boosters’ that drive gene overexpression directly in a CAR construct provides a simple and scalable strategy …
Convergent MurJ flippase inhibition by phage lysis proteins
Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10163-wA common mechanism of inhibition of the essential lipid II flippase MurJ by three distinct phage-encoded single-gene lysis proteins …
Clonal-aggregative multicellularity tuned by salinity in a choanoflagellate
Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10137-yThe choanoflagellate Choanoeca flexa forms motile and contractile cell monolayers purely clonally, purely aggregatively or through a combination of …
Pivoting colloidal assemblies exhibit mechanical metamaterial behaviour
Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10217-zA method is described for the manufacture of pivoting colloidal assemblies comprising rotating diamond and rotating triangle geometries that …
Squeaking at soft–rigid frictional interfaces
Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10132-3High-speed imaging reveals that the squeak of soft–rigid frictional interfaces, like sneakers sliding on a basketball court, arises from …
Pancreatic-targeted lipid nanoparticles based on organ capsule filtration
Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10158-7Elucidation of fundamental pancreatic-targeted mechanisms enables the development of lipid nanoparticles for the precise delivery of nucleic acid therapeutics …
Peripheral immune-inducer dendritic cells drive early-life allergic inflammation
Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10162-xEarly-life exposure to allergens triggers a distinct local mode of dendritic cell activation in neonatal skin without requiring migration …
Vectorized instructive signals in cortical dendrites
Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10190-7Mice learning a neurofeedback brain–computer interface task show neuron-specific teaching signals in cortical dendrites, consistent with a vectorized solution …
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