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CD51 delineates functionally distinct astrocyte subtypes in neural circuits
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11186-zCD51+ astrocytes promote synapse formation in the developing cortex, circuit plasticity in the hippocampus and circuit remodelling after stroke.
AI doctors’ orders come with a sky-high bill
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03320-8Large language models suggest more tests, referrals and medications than human physicians do, driving up the cost of care.
An environmentally regulated dichotomy in cell lineages of the root
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11179-yAn environment-regulated state is identified across multiple cell types at the root tip, revealing a shared dichotomy between cells …
A single archaeon couples long-chain fatty acid oxidation to methanogenesis
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11207-xMethanoglobus dolicholipophagus AA-75 is a thermophilic archaeon isolated from a Chinese petroleum reservoir that converts methanol into methane, carbon …
WEE1 opposes APC/C<sup>CDH1</sup> activity to promote S phase entry
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11188-xExperimental and modelling data indicate that WEE1 promotes re-entry of quiescent cells into the cell cycle, potentially explaining the …
Cold activates a BH2 metabolic network promoting longevity and proteostasis
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11152-9A multi-tissue signalling system links cold temperature to enhanced longevity and proteostasis in Caenorhabditis elegans.
Zeolite-catalysed olefin carbonylation based on tuning spatial confinement
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11183-2The use of zeolites with an appropriate pore structure combined with a high CO/olefin ratio is shown to catalyse …
The contribution of salt marshes to wave attenuation during extreme storms
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11145-8Salt marsh platforms resist erosion under extreme waves, but vegetation damage reduces wave attenuation; substantial wave attenuation by vegetation …
Multimodal precision diagnostics in clinical xenotransplantation
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11096-0Now that hyperacute rejection of pig xenografts can be reliably prevented, subtler immune-mediated graft injuries have emerged that conventional …
Fabric user interface can be worn on your sleeve — and machine-washed
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03064-5Touch-sensitive, light-emitting yarn can turn everyday clothing into washable, bendable user interfaces with dynamic graphics and versatile computing functions.
Robert Williamson obituary: geneticist who mapped genes for muscular dystrophy and cystic …
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03375-7Researcher and policy adviser who championed tests and treatments for genetic diseases.
A single antimatter particle in a cage opens door to ‘revolutionary’ physics
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03342-2Physicists trap and cool down positron for months to measure its ‘magnetic moment’ with extraordinary precision.
Large-scale single crystals printed layer by layer
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03257-yA 3D-printing method has made single crystals of metals and alloys in complex shapes and up to one metre …
Cave stalagmites document global patterns in monsoon rainfall over the past 450,000 …
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03285-8A 450,000-year stalagmite record of rainfall in the Amazon Basin , combined with existing Asian records, shows that the …
Worms live longer in cool conditions thanks to a muscle-derived molecule
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03066-3In nematodes, a metabolite induced by the cold links low temperatures to a body-wide signal that promotes longevity. This …
Can plants defend coasts against storms?
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03063-6Salt-marsh plants can protect inland areas against huge waves — but seemingly only up to a point, and big …
This is what the mysterious Denisovans looked like
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03360-0Archaeologists identified skull fragments from China as belonging to this group of ancient human relatives.
The Bursar
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03110-2A good way to learn?
Plastics embedded with enzymes degrade readily in the sea
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03282-xEmbedding enzymes that break down ester bonds into compostable polyesters enables rapid and complete biodegradation even in microbe-scarce environments. …
Huge mapping study reveals how your brain tracks what your body is …
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03334-2Signals in the insula region, deep in the brain, can make people feel hot, tingly and nauseous.
To heal sick cities, scientists and residents must work together
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03161-5Tolullah Oni has developed a platform to transfer the intellectual capital of African diaspora scholars back to the continent.
Surprise! White dwarf stars come in a rainbow of colours
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03319-1Analysis of some nearby stars shows that, despite their name, these bodies can be pink, yellow and more.
Using AI to offer personalized health advice
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03065-4The use of artificial-intelligence tools in medicine is increasing. What types of technology might be on the horizon and …
An AI tool improves weather forecasts up to a month ahead
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03077-0An innovative artificial-intelligence application enhances weather forecasting in the difficult subseasonal range, providing accurate forecasts of precipitation, temperature and …
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