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Latest news from trusted sources around the world
Scotland's assisted dying bill rejected after emotional debate
Scotland would have become the first part of the UK to legalise the process had MSPs backed the proposals.
Progress in reducing child deaths slows as 4.9 million children die before …
An estimated 4.9 million children died before their fifth birthday in 2024, including 2.3 million newborns, according to new estimates released today. Most of these …
Thymus health is a predictor of lifelong well-being and immunotherapy effectiveness
Nature, Published online: 18 March 2026; doi:10.1038/d41586-026-00633-6It was thought that the thymus serves its purpose for the immune system early in life. Insights about the …
An enzyme inside the bacterial-cell membrane chops up viral DNA on entry
Nature, Published online: 18 March 2026; doi:10.1038/d41586-026-00732-4When a virus infects a bacterial cell, the viral genome is the first component to be fully injected into …
CRISPR makes enhanced cancer-fighting immune cells inside mice
Nature, Published online: 18 March 2026; doi:10.1038/d41586-026-00857-6Gene-editing technique promises a potentially safer way to create CAR T cells with a simple injection.
Daily briefing: Funding calls plummet as NIH turns away from agency-directed science
Nature, Published online: 18 March 2026; doi:10.1038/d41586-026-00897-yThe US National Institutes of Health will now focus on ‘unsolicited’ research proposals driven by the interests of individual …
Our microbial ancestors were probably oxygen-tolerant
Nature, Published online: 18 March 2026; doi:10.1038/d41586-026-00718-2Genomic analysis has unexpectedly revealed that microorganisms called Asgard archaea, the closest relative of our cellular ancestors, can respire …
Brain’s protective barrier stays leaky for years after playing contact sports
Nature, Published online: 18 March 2026; doi:10.1038/d41586-026-00885-2Damage to the blood–brain barrier is linked to immune changes and cognitive decline.
Mystery of how plants make a family of medicinal molecules has been …
Nature, Published online: 18 March 2026; doi:10.1038/d41586-026-00790-8The cinchona alkaloids are a family of plant-derived compounds that include quinine, an antimalarial drug also used as the …
Quirky base pairing attracts rule-breaking enzymes to destroy microRNAs
Nature, Published online: 18 March 2026; doi:10.1038/d41586-026-00632-7MicroRNAs control gene expression by modulating the output and stability of messenger RNAs. How are these crucial regulators kept …
Static electricity is a big mystery — a jolt of fresh research …
Nature, Published online: 18 March 2026; doi:10.1038/d41586-026-00837-wThe familiar phenomenon has puzzled researchers for centuries, but experiments are finally making sense of its unruly behaviours.
A gene-editing method generates immunotherapeutic CAR T cells in the body
Nature, Published online: 18 March 2026; doi:10.1038/d41586-026-00634-5Laboratory-engineered immune cells called CAR T cells provide effective treatment for some cancers. Progress is being made towards creating …
Leading the charge to explain static electricity
Nature, Published online: 18 March 2026; doi:10.1038/d41586-026-00839-8There’s a shocking lack of understanding of the physics underlying this commonplace phenomenon, but researchers are on the case.
Hair-raising: how carbon contamination can drive static charging
Nature, Published online: 18 March 2026; doi:10.1038/d41586-026-00631-8Objects made from the same insulator can sometimes acquire different charges when rubbed together, owing to a thin layer …
Genome editing that avoids immune detection to integrate large DNA sequences
Nature, Published online: 18 March 2026; doi:10.1038/d41586-026-00730-6A genome-editing approach called INSTALL combines single-stranded DNA molecules that evade immune detection with a short double-stranded region that …
Climate snapshots trapped in ancient ice tell a surprising story
Nature, Published online: 18 March 2026; doi:10.1038/d41586-026-00636-3Antarctic ice cores hint that changes in the ocean might have played a larger part than have greenhouse gases …
Catabolism of extracellular glutathione supplies cysteine to support tumours
Nature, Published online: 18 March 2026; doi:10.1038/s41586-026-10268-2Catabolism of extracellular glutathione by γ-glutamyltransferases supports tumour growth and survival, and pharmacological targeting of these enzymes slows tumour …
A strong constraint on radiative forcing of well-mixed greenhouse gases
Nature, Published online: 18 March 2026; doi:10.1038/s41586-026-10289-xComparing line-by-line transfer simulations using the radiation code GRTcode with regressions against satellite-observed ongoing longwave radiation shows that instantaneous …
Climbing fibres recruit disinhibition to enhance Purkinje cell calcium signals
Nature, Published online: 18 March 2026; doi:10.1038/s41586-026-10220-4Synchronous activation of climbing fibres engages disinhibitory circuitry to promote large dendritic calcium signals in Purkinje cells that are …
Adventitious carbon breaks symmetry in oxide contact electrification
Nature, Published online: 18 March 2026; doi:10.1038/s41586-025-10088-wBy measuring charge exchange in a sphere/plate pair composed of identical amorphous silicon dioxide and controlling charging polarity using …
The E3 ubiquitin ligase mechanism specifying targeted microRNA degradation
Nature, Published online: 18 March 2026; doi:10.1038/s41586-026-10232-0Target-directed microRNA degradation is driven by the atypical ZSWIM8–CUL3 E3 ubiquitin ligase that uses a two-RNA-factor authentication mechanism to …
Integrated photonic neural network with on-chip backpropagation training
Nature, Published online: 18 March 2026; doi:10.1038/s41586-026-10262-8An integrated photonic deep neural network was trained end-to-end with on-chip gradient-descent backpropagation, and all linear and nonlinear computations …
Biosynthesis of cinchona alkaloids
Nature, Published online: 18 March 2026; doi:10.1038/s41586-026-10227-xA combination of isotopic labelling, gene silencing, single-nucleus RNA sequencing and comparative transcriptomics reveal the genes that mediate the …
Proteasome-guided haem signalling axis contributes to T cell exhaustion
Nature, Published online: 18 March 2026; doi:10.1038/s41586-026-10250-yExhausted CD8+ T cells increase proteasome activity due to the accumulation of depolarized mitochondria, which drives the selective degradation …
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