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Science Nature News
Dynamics of circulating tumour DNA can guide treatment decisions for improved outcomes

Nature, Published online: 11 March 2026; doi:10.1038/d41586-026-00715-5A phase II trial shows that the risk of cancer recurrence as reflected by circulating tumour DNA can guide …

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A silicon chip that enables the creation of 4D cameras

Nature, Published online: 11 March 2026; doi:10.1038/d41586-026-00727-1The development of an affordable, low-power and scalable sensor to map the position and velocity of 3D objects in …

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Photonic ‘ski jump’ steers light beam from silicon chip

Nature, Published online: 11 March 2026; doi:10.1038/d41586-026-00489-wChip-based beam scanners use tiny electrically controlled cantilevers instead of moving mirrors to control the direction of light projected …

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Using mosquitoes to vaccinate bats could curb the spread of deadly diseases

Nature, Published online: 11 March 2026; doi:10.1038/d41586-026-00795-3But scientists say there are practical and ethical challenges to overcome before the strategy could be deployed in real-world …

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Quantum entanglement as a tool to image distant astronomical objects

Nature, Published online: 11 March 2026; doi:10.1038/d41586-026-00724-4Particles entangled over long distances can, in theory, improve the sensitivity of long-baseline interferometers that are observing weak thermal …

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How an all-female fish species defies evolutionary expectations

Nature, Published online: 11 March 2026; doi:10.1038/d41586-026-00493-0Asexual reproduction should be an evolutionary dead end. A study of asexual fish shows that a genetic ‘copy and …

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Ultra-bright supernova wobbles like a spinning top

Nature, Published online: 11 March 2026; doi:10.1038/d41586-026-00490-3Oscillations in the brightness of a ‘superluminous’ supernova reveal it to be powered by a magnetized neutron star that …

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Memory loss is fuelled by gut microbes in ageing mice

Nature, Published online: 11 March 2026; doi:10.1038/d41586-026-00768-6If confirmed in people, the finding might lead to gut-targeted therapies that could reverse cognitive decline.

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Daily briefing: ‘Virtual cell’ simulates nearly every chemical reaction in the real …

Nature, Published online: 11 March 2026; doi:10.1038/d41586-026-00815-2A new simulation models processes such as DNA replication and cell division in a virtual bacterial cell. Plus, China …

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A mechanism to initiate emergency type 2 myelopoiesis

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10256-6Myelopoiesis in response to a parasitic worm infection and the mechanism selective to this form of parasite are revealed.

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Gene conversion empowers natural selection in a clonal fish species

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10180-9Analysis of the asexually reproducing Amazon molly Poecilia formosa and its sexually reproducing progenitors Poecilia mexicana and Poecilia latipinna …

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Risk-adaptive therapy guided by dynamic ctDNA in nasopharyngeal carcinoma

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10244-wA clinical trial testing whether monitoring ctDNA clearance during treatment for nasopharyngeal cancer could be used to inform decisions …

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Ageing promotes metastasis via activation of the integrated stress response

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10216-0Ageing reprograms the evolutionary trajectory of KRAS-driven lung adenocarcinoma, limiting primary tumour growth while promoting metastatic dissemination through epigenetic …

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Natural maternal immunity protects neonates from <i>Escherichia coli</i> sepsis

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10225-zNeonatal sepsis caused by Escherichia coli is associated with reduced transfer of pathogen-specific maternal antibodies and, in a mouse …

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Immune evasive DNA donors and recombinases license kilobase-scale writing

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10241-zINSTALL overcomes fundamental challenges for DNA delivery and integration methods by synergizing immune-stealth nucleic acids with recombinases to enable …

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A big-push community intervention reduced rates of child marriage by 80%

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10206-2A community-wide intervention in northern Nigeria reduced rates of child marriage from 79% to 14%, showing that bundled, big-push …

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Nanophotonic waveguide chip-to-world beam scanning

Nature, Published online: 11 March 2026; doi:10.1038/s41586-025-10038-6A monolithically integrated photonic ski-jump enables scalable, diffraction-limited 2D beam scanning from photonic chips, achieving ultrahigh spot rates, compact …

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B cell imprinting in children impairs antibodies to the haemagglutinin stalk

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10248-6Imprinting by influenza viruses can cause a deleterious shift of nearly the entire memory recall response against key, conserved …

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A sorghum pangenome reference improves global crop trait discovery

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10229-9A pangenome reference for the phenotypically diverse crop sorghum aims to help accelerate future efforts to breed crops that …

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Assembly of helper NLR resistosome clusters upon activation of a coiled-coil NLR

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10215-1SUMM2, a coiled-coil NLR, promotes the assembly of higher-order resistosome clusters to initiate cell death in plants.

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Intestinal interoceptive dysfunction drives age-associated cognitive decline

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10191-6Age-related microbiome changes increase medium-chain fatty acid-producing bacteria, driving GPR84-mediated myeloid inflammation, impaired vagal signalling and hippocampal dysfunction; targeting …

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Snapshots of the dynamic basis of NTSR1 G protein subtype promiscuity

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10120-7Time-resolved cryo-electron microscopy during activation of Gαi1βγ and Gα11βγ heterotrimers bound to NTSR1 enables isolation of multiple transient complexes …

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Facile induction of immune tolerance by an interleukin-2–TGFβ surrogate agonist

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10208-0A fusion protein designed to comprise IL-2 and a helminth-derived TGFβ mimic activates IL-2 and TGFβ signalling pathways in …

Science Nature News
Lense–Thirring precessing magnetar engine drives a superluminous supernova

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10151-0Observations of a nearby type I superluminous supernova showing oscillating light-curve bumps provide evidence of a centrally located magnetar …

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