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Reimagining research papers as interactive and reliable AI agents
Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11044-yPaper2Agent converts research papers into interactive artificial intelligence agents by turning manuscripts, code and data into model context protocol-based …
Mitochondrial fission factor senses and governs ferroptosis
Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11020-6The mitochondrial–peroxisomal fission adaptor MFF is identified as a selective pro-ferroptotic mediator, and the newly developed MFF–SPARK sensor enables …
Developmental xenocortication using human-derived organoids in mice
Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11032-2Xenocortication with human neurons enables circuit- and behaviour-level analysis of neurodevelopment in mice.
Development of a random background to understand ligand optimization
Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11013-5An approach to improve efficiency and establish a background expectation for ligand potency optimization is described.
Transplanted human brain-tissue takes root in mice without a cortex
Nature, Published online: 16 September 2026; doi:10.1038/d41586-026-02927-1Extensive cellular integration might provide platform for in vivo testing of new therapies — plus, the AI tool that …
Why most stars don’t have outbursts like the Sun’s
Nature, Published online: 16 September 2026; doi:10.1038/d41586-026-02833-6A strong magnetic field can disrupt a star’s ability to produce the fountains of matter called coronal mass ejections.
Mechanisms of Transcriptional Regulation by Salicylic Acid Receptors
Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11123-0Mechanisms of Transcriptional Regulation by Salicylic Acid Receptors
Inflection points and transitions in Alzheimer’s disease
Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11110-5Inflection points and transitions in Alzheimer’s disease
These bizarre, much-coveted microbes are revealing the origins of complex life
Nature, Published online: 16 September 2026; doi:10.1038/d41586-026-02849-yResearchers are racing to culture a menagerie of exotic organisms and finding lots of surprises along the way.
Map of brain ‘microproteins’ could offer new clues to Alzheimer’s disease
Nature, Published online: 16 September 2026; doi:10.1038/d41586-026-02914-6Researchers detect more than 1,000 overlooked microproteins in human brain tissue, including some that are altered in Alzheimer’s disease.
Daily briefing: Reading for pleasure linked to big brain benefits
Nature, Published online: 15 September 2026; doi:10.1038/d41586-026-02924-4Evidence that reading for fun is related to structural brain changes, improved mental health and reduced risk of cognitive …
‘Stomach bugs’ send protective immune cells rushing from gut to brain
Nature, Published online: 15 September 2026; doi:10.1038/d41586-026-02891-wVoyaging gut-derived immune cells ‘remember’ past stomach infections in mice.
Cities and countryside are intimately linked — green initiatives must recognize that
Nature, Published online: 15 September 2026; doi:10.1038/d41586-026-02853-2Urban areas depend on resources from the land that surrounds them. Managing regions in their entirety is the best …
Underground hydrogen could spur a green-energy revolution — if companies can find …
Nature, Published online: 15 September 2026; doi:10.1038/d41586-026-02850-5Firms are racing to drill for hydrogen in hopes of finding a dirt-cheap green-energy source.
Global inequality panel is a chance for research to change lives
Nature, Published online: 15 September 2026; doi:10.1038/d41586-026-02885-8The scientific panel is welcomed. It must now invite all interested researchers to participate.
The geometric genius of René Descartes
Nature, Published online: 15 September 2026; doi:10.1038/d41586-026-02723-xThe achievements of a visionary mathematician, and a trip to the National Air and Space Museum in Washington DC, …
Author Correction: Erythropoietin receptor on cDC1s dictates immune tolerance
Nature, Published online: 15 September 2026; doi:10.1038/s41586-026-11137-8Author Correction: Erythropoietin receptor on cDC1s dictates immune tolerance
Quality control of glycogen through direct ubiquitylation by RNF213
Nature, Published online: 15 September 2026; doi:10.1038/s41586-026-11139-6Quality control of glycogen through direct ubiquitylation by RNF213
CRISPR crops are coming to Europe — why bolder would be better
Nature, Published online: 15 September 2026; doi:10.1038/d41586-026-02848-zFor farmers and consumers to reap the benefits, guidelines for farming gene-edited plants must be implemented with careful thought.
Why the NIH must resist the metrics trap
Nature, Published online: 15 September 2026; doi:10.1038/d41586-026-02906-6Why the NIH must resist the metrics trap
Make AI traceable before it shapes global climate assessments
Nature, Published online: 15 September 2026; doi:10.1038/d41586-026-02905-7Make AI traceable before it shapes global climate assessments
Why Nepal floods resulted in a disaster even after satellites spotted danger
Nature, Published online: 15 September 2026; doi:10.1038/d41586-026-02907-5Why Nepal floods resulted in a disaster even after satellites spotted danger
A wake-up call: diversify global research funding
Nature, Published online: 15 September 2026; doi:10.1038/d41586-026-02904-8A wake-up call: diversify global research funding
Daily briefing: How this year’s super El Niño is different
Nature, Published online: 14 September 2026; doi:10.1038/d41586-026-02915-5Climate change makes the event difficult to predict. Plus, signs of success from an early trial of an osteoporosis …
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