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Aberrant excitatory neuronal ERBB4 promotes Alzheimer’s disease pathology
Nature, Published online: 26 August 2026; doi:10.1038/s41586-026-10964-zNeuroinflammation alone may be dispensable for early synapse loss in Alzheimer’s disease.
Critical zone processes limit alkalinity export from natural basaltic systems
Nature, Published online: 26 August 2026; doi:10.1038/s41586-026-10936-3Observations from natural volcanic watersheds demonstrate attenuation of alkalinity fluxes along the complete reactive pathways from soil to river …
A binding-to-release strategy for targeted anticancer drug delivery
Nature, Published online: 26 August 2026; doi:10.1038/s41586-026-10971-0A binding-to-release drug conjugate strategy enables targeted payload release without cellular internalization, improving tumour specificity, efficacy and expanding therapeutic …
Synergistic degradation of fucoidans in the ocean
Nature, Published online: 26 August 2026; doi:10.1038/s41586-026-10980-zEfficient degradation of fucoidans depends on complementary bacterial guilds that cooperatively break backbone and side-chain sugars, revealing a conserved, …
Tidal tomography reveals a thermal anomaly beneath Mars’s crustal dichotomy
Nature, Published online: 26 August 2026; doi:10.1038/s41586-026-10893-xAnalysis of tracking data from Mars orbiters reveals time-variable gravity field behaviour reflecting the structure underlying the Martian crustal …
3D bulk-resolved <i>g</i>-wave altermagnetic order parameter in CrSb
Nature, Published online: 26 August 2026; doi:10.1038/s41586-026-10902-zQuantum oscillation measurements map the g-wave altermagnetic order parameter in CrSb, establishing it as a prototypical unconventional magnet with …
Amphibious stem-insect sheds light on colonization of land
Nature, Published online: 26 August 2026; doi:10.1038/s41586-026-10961-2Restudy of a challenging fossil using cross-polarized light imaging and phylogenetic reconstruction identifies Chosha praecursor, a probable early-diverging insect, …
Cell-type-specific eQTLs underlie the genetic architecture of complex traits
Nature, Published online: 26 August 2026; doi:10.1038/s41586-026-10577-6Single-cell RNA-sequencing shows that cell-type-specific expression quantitative trait loci drive much of complex trait heritability, highlighting cell-type-specific gene regulation …
Ultrafast and reference-free sequence discovery in single-cell data
Nature, Published online: 26 August 2026; doi:10.1038/s41586-026-10975-wMalva enables ultrafast, reference-free searching of raw single-cell sequences across millions of cells, transforming static transcriptomic atlases into dynamic …
Systems vaccinology and the architecture of human immunity
Nature, Published online: 26 August 2026; doi:10.1038/s41586-026-10753-8A review of the current state of the field of systems vaccinology discusses the challenges in translating insights into …
Insights into longevity and virus-driven adaptation from <i>Myotis</i> bat genomes
Nature, Published online: 26 August 2026; doi:10.1038/s41586-026-10932-7Comparative and functional analyses of Myotis bats uncover unique patterns of adaptation in virus-interacting proteins and longevity-associated pathways, linking …
Automated prototyping of genetic codes
Nature, Published online: 26 August 2026; doi:10.1038/s41586-026-10949-yA robotic, cell–free platform rapidly prototypes redesigned genetic codes, enabling the translation of proteins with reassigned codons and non-standard …
Using nuclear waste to power space missions
Nature, Published online: 26 August 2026; doi:10.1038/d41586-026-02514-4Researchers plan to use radioactive isotopes to power systems on a future Mars rover.
Highest-ever ocean temperatures recorded as El Niño intensifies
Nature, Published online: 26 August 2026; doi:10.1038/d41586-026-02681-4Why extreme temperatures are expected to weaken ocean carbon sinks — plus, how mitochondrial injections could treat vision loss.
South Africa’s ‘registration law’ for scientists could be a template for the …
Nature, Published online: 26 August 2026; doi:10.1038/d41586-026-02568-4The plan to force some scientists to register with a professional body could protect people and the environment, but …
More than 18,000 questionable images found in antibody catalogues of 15 companies
Nature, Published online: 25 August 2026; doi:10.1038/d41586-026-02635-wScience sleuth’s findings raise questions for researchers working to improve the reliability of commercial antibodies.
These rodent OnlyFans stars are helping to fund scientific research
Nature, Published online: 25 August 2026; doi:10.1038/d41586-026-02550-0The platform, mostly known for its adult content, has provided a financial lifeline amid US federal-funding uncertainty. And now …
Daily briefing: Billion-dollar machine aims to set a fusion-energy record
Nature, Published online: 25 August 2026; doi:10.1038/d41586-026-02673-4The push to develop fusion energy, how China is changing the shape of global health and why scientists are …
AI-detection tools have made huge leaps forward — how good are they?
Nature, Published online: 25 August 2026; doi:10.1038/d41586-026-02569-3Scientists and publishers are testing a new breed of software that promises impressive accuracy at spotting AI-written text.
How tech-enhanced sleep could improve rest but erode privacy
Nature, Published online: 25 August 2026; doi:10.1038/d41586-026-02573-7Technologies that promise better-than-usual sleep could improve people’s performance and health but also turn the need for rest into …
China is changing the shape of global health. The terms are still …
Nature, Published online: 25 August 2026; doi:10.1038/d41586-026-02622-1Health-care partnerships can provide other nations with cheap diagnostics, medicines and more — but global institutions should help to …
How one researcher captured a vanished world of UK government science
Nature, Published online: 25 August 2026; doi:10.1038/d41586-026-02094-3Oral historian Emmeline Ledgerwood’s PhD investigated how privatization affected civil-service scientists at the end of the twentieth century.
A guide to securing your first research fellowship: what reviewers are looking …
Nature, Published online: 25 August 2026; doi:10.1038/d41586-026-02115-1How early-career researchers can strengthen their track record, boost their research proposal and assess institutional fit.
The brain struggles to make new neurons in people with depression
Nature, Published online: 25 August 2026; doi:10.1038/d41586-026-02661-8High resolution, wide-coverage map of the hippocampus reveals possible pathways for therapy.
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